If you have been exploring natural, science-backed ways to refresh your skin without surgery or synthetic fillers, you may have come across PRP and PRF aesthetic treatment. These regenerative therapies are gaining popularity for their ability to use your body’s own healing factors to promote smoother, healthier, more radiant skin. But what exactly are they, and how do they work?
In this Ask the Expert guide, we’ll break down the science behind platelet-rich plasma therapy and platelet-rich fibrin facials, explain the differences between PRP vs PRF, and share why these innovative treatments are becoming a go-to for women across St Ives and the Huntingdonshire area.
What is PRP and how does it work in skincare?
Platelet-rich plasma (PRP) is a treatment that involves drawing a small amount of your blood, processing it in a centrifuge to concentrate the platelets, and re-injecting that plasma into the skin. Platelets contain growth factors that stimulate collagen production, tissue repair, and cell renewal. This makes PRP especially beneficial for:
- Improving skin texture and tone
- Reducing fine lines and wrinkles
- Diminishing dark under-eye circles
- Smoothing acne scars
PRP is commonly known for its use in the so-called “vampire facial” and has decades of medical use behind it in sports medicine and wound healing. In aesthetics, it has become an excellent option for clients seeking natural anti-ageing results without artificial substances.
What is PRF and how is it different from PRP?
Platelet-rich fibrin (PRF) is considered the next generation of PRP. While it also uses your blood, the processing is slower and gentler, preserving more regenerative cells like white blood cells and stem cells. PRF creates a fibrin matrix, a gel-like substance that allows the release of growth factors over a longer period.
Key differences between PRP and PRF:
- Processing time: PRF is spun at a lower speed, preserving more healing cells
- Additives: PRP sometimes contains anticoagulants; PRF is 100% natural with no additives
- Longevity: PRF releases growth factors slowly over several days, offering longer-term regeneration
- Consistency: PRF is thicker and acts more like a natural filler
At Tweaks Aesthetics, we use PRF in advanced treatments such as PRF EZ Gel, which combines platelet-rich fibrin with heat-treated albumin to create a powerful, injectable volumiser from your own blood.

Who can benefit from PRP and PRF aesthetic treatments?
These treatments are ideal for women in their 30s to 60s who are noticing:
- Skin laxity and fine lines
- Dullness or uneven texture
- Loss of facial volume
- Early signs of ageing
- Acne scarring or sun damage
If you want visible rejuvenation without the commitment of synthetic injectables, PRP and PRF offer a more natural alternative. They are also excellent for clients interested in combination therapies with microneedling, skin boosters, or dermal fillers.
What does a PRP or PRF session involve at Tweaks Aesthetics?
We begin with a consultation to assess your skin and treatment goals. Once suitability is confirmed, the treatment process is as follows:
- A small blood draw (usually from the arm)
- Centrifugation to separate plasma (PRP) or fibrin-rich gel (PRF)
- Application or injection into targeted areas of the face
- Post-treatment care and hydration advice
Most sessions last about 60 minutes, and downtime is minimal. You may experience mild redness or swelling for a day or two.

How many treatments will I need?
Results vary depending on your skin condition and goals. Most clients benefit from 3 sessions spaced 4–6 weeks apart, followed by maintenance every 6–12 months. As PRF and PRP work gradually, results appear subtly and improve over time.
Why choose Tweaks Aesthetics for PRP and PRF in St Ives?
All PRP and PRF treatments at Tweaks Aesthetics are carried out by trained practitioners with over 20 years’ experience in clinical care. We’ve completed advanced PRP/PRF training through The Cosmetic College, ensuring every procedure is delivered safely and in line with the latest techniques.
Rather than follow generic protocols, we tailor each session to your skin, your goals, and what will deliver the most natural, regenerative results over time.
Curious about natural skin rejuvenation?
PRP and PRF treatments offer a personalised, science-led way to refresh your skin without synthetic fillers. If you’re in St Ives or the surrounding area, we’d be happy to guide you through your options.
Book your personalised consultation at Tweaks Aesthetics in St Ives today.